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Anthropic CEO. https://t.co/qXHIf42RIT

Industry veterans, degenerate gamblers & besties Chamath Palihapitiya, Jason Calacanis, David Sacks & David Friedberg cover all things economic, tech, political, social & poker.
Dario Amodei is in the headlines this week as Anthropic’s reported revenue run rate jumps past $65 billion ahead of a potential IPO, signaling real competitive momentum in frontier AI. He has not been on All-In before, according to the show’s episode listings, so hearing him unfiltered here would be genuinely new for the audience.
At the same time, the AI safety fight is intensifying, with major labs throttling some releases and Anthropic publicly inviting “hard questions” about its models and policies. Amodei’s answers now could influence how quickly powerful systems roll out, who gets access, and what safeguards are adopted.
He is staking a nuanced position on open‑weight models, saying Anthropic has never backed a blanket ban and that smaller non‑dangerous models are a public good, while also warning that AI faces a crisis of public trust. That combination of hard numbers and hard choices is exactly what All-In’s operator and investor audience needs to interrogate today.
Back this booking so the Besties can press Amodei on near‑term model decisions like Anthropic’s recent Fable 5 redeploy and rumored updates, and help shape how AI gets built and governed right now. Support this nomination.
Nomination created on August 17, 2026
Get Dario Amodei on All-In with Chamath, Jason, Sacks & Friedberg!