Dive into the cutting-edge worlds of technology and science with Dwarkesh Patel's meticulously researched interviews that bring together brilliant minds to unpack revolutionary ideas in AI, biotech, and beyond. Each episode delivers profound, thought-provoking conversations that challenge conventional wisdom and illuminate the paths shaping humanity's future.

Dwarkesh Podcast

https://x.com/LiveFromVR/status/1753206263360475427

OpenAI's cybersecurity briefing with U.S. lawmakers: Addressing AI model risks

OpenAI's strategic shift: Loosening ties with Microsoft amid Musk's lawsuit

OpenAI's hardware ambitions: Exploring a partnership with Qualcomm

Elon Musk's lawsuit against OpenAI: Allegations of mission betrayal

OpenAI's internal challenges: Missed targets and market impact

OpenAI's response to the Canada school shooting lawsuit: CEO's apology

Part podcast, part cultural time capsule, The Joe Rogan Experience is the most listened to podcast in the world, where curiosity runs long and conversations go anywhere. From comedians and scientists to fighters, philosophers, and wildcards, Rogan explores everything from human performance to conspiracy theories with raw curiosity and zero filters. It’s unpredictable, unpolished, and somehow essential — the internet’s campfire for people who just want to hear what happens when you let the mics roll.

The Joe Rogan Experience

This is what the news should sound like. The biggest stories of our time, told by the best journalists in the world. Hosted by Michael Barbaro, Rachel Abrams and Natalie Kitroeff. Twenty minutes a day, five days a week, ready by 6 a.m. Subscribe today at nytimes.com/podcasts or on Apple Podcasts and Spotify. You can also subscribe via your favorite podcast app here https://www.nytimes.com/activate-access/audio?source=podcatcher. For more podcasts and narrated articles, download The New York Times app at nytimes.com/app.

The Daily

A raw, unfiltered deep dive into the minds of people who’ve lived on the edge—special operators, intelligence insiders, survivors, and truth-tellers who’ve seen what most never will. This isn’t polished media training or surface-level storytelling; it’s long-form, sit-down conversations where nothing is rushed and nothing important is edited out. Expect hard-earned perspective, uncomfortable truths, and a level of candor that cuts through the noise of modern media. It’s less about entertainment and more about understanding what really happens behind the curtain—and what it does to the people who’ve been there.

Shawn Ryan Show

One of India’s biggest podcasts, WTF is with Nikhil Kamath brings together an unlikely mix of global power players and deep thinkers for conversations that cut beneath surface-level success. From billionaires and industry leaders to philosophers and cultural voices, the guest list reflects a show operating at the intersection of business, influence, and introspection. Nikhil Kamath, co-founder of Zerodha, approaches each discussion less like an interviewer and more like an operator trying to make sense of the world in real time — unpacking wealth, ambition, meaning, and the contradictions that come with building at scale. It’s expansive, candid, and quietly ambitious, capturing a generation of builders who are no longer just chasing success, but questioning what it’s for.

WTF is with Nikhil Kamath

The Tucker Carlson Show is your beacon of free speech and honest reporting in a media landscape dominated by misinformation. The only solution to ending the propaganda spiral is by telling the truth. That's our job. Every day. No matter what.

The Tucker Carlson Show

Join four entrepreneur and investor friends—Arman Assadi, Nick Urbani, Stephen Cesaro, and Eric Johanson—as they dive into the intersection of money, meaning, and fulfillment in the Alfalfa Podcast. Broadcasting live every Wednesday, this community-driven show offers an intellectual rollercoaster of shenanigans, insights, and discussions that blend business acumen with philosophical exploration. With a vibrant Discord community hailed as 'the best place on the internet,' it's the perfect blend of wealth-building strategies and life-affirming wisdom for those seeking an edge in both finances and personal growth.

Alfalfa Podcast

“Hard Fork” is a show about the future that’s already here. Each week, journalists Kevin Roose and Casey Newton explore and make sense of the latest in the rapidly changing world of tech. Subscribe today at nytimes.com/podcasts or on Apple Podcasts and Spotify. You can also subscribe via your favorite podcast app here https://www.nytimes.com/activate-access/audio?source=podcatcher. For more podcasts and narrated articles, download The New York Times app at nytimes.com/app.

Hard Fork

Ai Ai Ai

Zero Knowledge is a podcast which goes deep into the tech that will power the emerging decentralised web and the community building this. Covering the latest in zero knowledge research and applications, the open web as well as future technologies and paradigms that promise to change the way we interact — and transact — with one another online.Zero Knowledge is hosted by Anna RoseFollow the show at @ZeroKnowledgefm (https://twitter.com/zeroknowledgefm) or @AnnaRRose (https://twitter.com/AnnaRRose) If you like the Zero Knowledge Podcast: Join us on Telegram (https://t.me/joinchat/TORo7aknkYNLHmCM)Support our Gitcoin Grant (https://gitcoin.co/grants/38/zero-knowledge-podcast)Support us on Patreon (https://www.patreon.com/zeroknowledge)Or directly here: ETH: 0x4BF66E52f3009Cd138e48f142D47661037160001BTC: 1cafekGa3podM4fBxPSQc6RCEXQNTK8ZzZEC: t1R2bujRF3Hzte9ALHpMJvY8t5kb9ut9SpQDOT: 14zPzb7ihiBeaUn9jdPW9cHKGBd9qtTuJE75hhW2CvzLh6rT

Zero Knowledge

Lightcone Podcast ignites techno-optimism among technical founders by exploring the latest breakthroughs in AI, biotech, and beyond through conversations with Y Combinator experts. Hosted by Garry Tan, Diana Hu, Harj Taggar, and Jared Friedman, it delivers inspiring insights on building scalable startups and shaping a brighter future with innovative tech. Perfect for entrepreneurs eager to turn bold ideas into world-changing realities.

Lightcone Podcast

Sam Parr and Shaan Puri brainstorm new business ideas based on trends & opportunities they see in the market. Sometimes they bring on famous guests to brainstorm with them.

My First Million

Join neuroscientist, philosopher, and five-time New York Times best-selling author Sam Harris as he explores important and controversial questions about the mind, society, current events, moral philosophy, religion, and rationality—with an overarching focus on how a growing understanding of ourselves and the world is changing our sense of how we should live. Sam is also the creator of the Waking Up app. Combining Sam’s decades of mindfulness practice, profound wisdom from varied philosophical and contemplative traditions, and a commitment to a secular, scientific worldview, Waking Up is a resource for anyone interested in living a more examined, fulfilling life—and a new operating system for the mind. Waking Up offers free subscriptions to anyone who can’t afford one, and donates a minimum of 10% of profits to the most effective charities around the world. To learn more, please go to WakingUp.com.  Sam Harris received a degree in philosophy from Stanford University and a Ph.D. in ne

Making Sense with Sam Harris

Industry veterans, degenerate gamblers & besties Chamath Palihapitiya, Jason Calacanis, David Sacks & David Friedberg cover all things economic, tech, political, social & poker.

All-In with Chamath, Jason, Sacks & Friedberg

Decoder is a show from The Verge about big ideas — and other problems. Verge editor-in-chief Nilay Patel talks to a diverse cast of innovators and policymakers at the frontiers of business and technology to reveal how they’re navigating an ever-changing landscape, what keeps them up at night, and what it all means for our shared future.

Decoder with Nilay Patel

Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday.If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.

Crime Junkie

A high-voltage conversation factory led by Patrick Bet-David, where business, politics, and culture collide in long-form debates that actually go somewhere. It’s part boardroom, part barbershop—smart, confrontational, and grounded in an entrepreneurial lens that questions everything from power structures to personal responsibility. You’ll hear unapologetic perspectives, sharp analysis, and moments that veer from strategic insight to philosophical detour—all brought to life by a host who’s built companies, challenged narratives, and refuses to dumb things down.

PBD Podcast

This week in AI focuses on AI demos & interviews with AI's top personalities.

This Week in AI

Conversations about science, technology, history, philosophy and the nature of intelligence, consciousness, love, and power. Lex is an AI researcher at MIT and beyond.

Lex Fridman Podcast

In an era where AI agents automate workflows, hyper-personalization defines user experiences, and product-led growth demands outcome ownership, this essential weekly deep dive distills battle-tested tactics from top leaders at trillion-dollar tech giants and explosive startups—like AI coding pioneers and $200M ARR scalers—unpacking concrete frameworks from vibe coding vs. agentic AI to negotiation playbooks and burnout-proof leadership, arming PMs, founders, and growth hackers with steps to prototype faster, retain users, and hit PMF in competitive markets, all backed by its proven 4.9-star rating, 1.4K+ reviews, and top-10 tech podcast status as the playbook for 2026's high-stakes innovation game.

Lenny's Podcast: Product | Career | Growth

Painkiller Already is a weekly podcast featuring: Woody, Kyle also known as FPS Russia, and Taylor. Commonly referred to as PKA, the podcast has been steam-rolling through the airwaves & YouTube since early 2010.PKA discusses current events, news, relives comedic stories and gives their perspective on life while throwing in their comedic twist to all discussions

Painkiller Already

Contrary to expectations of rapid depreciation due to technological advancements, an H100 GPU is worth more today than three years ago because it can now run more advanced AI models that generate significantly higher value, such as GPT-5.4 compared to GPT-4. This dynamic highlights how compute value increases with model improvements in a capacity-constrained environment, benefiting early committers like OpenAI over more conservative players like Anthropic.

By 2030, the primary bottleneck for scaling AI compute will shift to ASML's EUV lithography tools, with production limits potentially capping cumulative AI chip capacity at around 200 gigawatts, challenging ambitious goals like Sam Altman's vision of deploying a gigawatt per week amid the ongoing AI boom.

Despite ambitious demands for massive AI compute scaling, such as Elon Musk's 100 gigawatts per year by 2028, the semiconductor supply chain lags far behind due to insufficient AGI-driven production ramps and architectural inefficiencies, making reliance on older 7nm processes inadequate for bridging the gap. This highlights a critical bottleneck in AI advancement, where performance differences between chip generations can reach 20x due to networking and data movement constraints, not just raw FLOPS.

Why is TSMC allocating the majority of its 3nm process capacity to Nvidia rather than diversifying among competitors like Google or Amazon to fracture the market and maintain leverage?

What prevents ASML from significantly increasing its production of EUV tools beyond 100 per year by 2030, despite the explosive demand for AI chips?

Given the compounding performance advantages of newer chip architectures, what fraction of the demanded AI compute could realistically be achieved by repurposing older 7nm fabs, and under what economic conditions would this become viable?

Get Sam Altman on Dwarkesh Podcast

The Case for This Conversation

What People Are Saying

Key Catalysts

Updates

Shape What Gets Discussed

Supporters

Featured Videos

Be the first to add your voice to this conversation

More voices on Dwarkesh Podcast

Vaclav Smil

Karl Friston

Steven Byrnes

Where else should Sam Altman appear?

Sam Altman

Sam Altman

Sam Altman

You Might Also Enjoy